ON THE QUESTION OF THE NECESSITY OF NORMATING BIO-TRANSFORMED SUBSTANCES MEDICINAL PREPARATIONS IN OBJECTS OF THE ENVIRONMENT (SHORT MESSAGE)

Аннотация

After entering the body, medications are subjected to a cascade of interrelated biochemical reactions,
which result in not only is the pharmacological effect achieved, but also the formation of the biotransformation
products. Theses chemicals ultimately wind up in waste water, where they are also exposed a whole complex of
abiotic and biotic processes. As a result, chemical compounds with new properties can be formed, able to change
physiological, biochemical, genetic and other parameters living organisms and to enter the food chain into the human
body. Therefore, it can be argued about the urgent problem on the necessity of predicting and understanding
biotransformed products of medicinal products in environmental objects, and including wastewater, which will
determine the impact of the risks health risks, expand (supplement) the standards of environmental pollution and
define a strategy for finding and developing new drugs.